Application

NMP was used:
 as an aqueous physical solvent to measure the molar heat capacities
 in the synthesis of Nafion/SiO2 nanocomposite membranes.
 in the synthesis of N-Butyl-N,N-dimethyl chitosan iodide (QCh).
 as an inducer to demonstrate phenotypic resistance to Chloramphenicol and ampicillin in Escherichia coli K-12 starins.
 used as polar solvent inducer for erythroleukemic cell differentiation.
 as a blocking reagent in microarray manufacturing.

General description

NMP, effective solvent for organic and inorganic compounds. Tertiary amides in H-bond basicity are decreased by bulky substituents on carbon than bulky substituents on nitrogen. It is also an effective solvent for the decarbonylation of aldehydes. It exhibits as reagent and amidines formed from NMP exist as amidine-enediamine tautomers. As cosolvent it has ability to enhance the reactivity of other reagents.